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Virus Origin: Genome Analysis of the New Wuhan Coronavirus Found Viral Sequences Suspicious of Laboratory Engineering

Dr. Lyons-Weiler, the founder and CEO of the Institute for Pure and Applied Knowledge (IPAK), published an article stating that medical research found evidence that might suggest the novel coronavirus in China could come out from a laboratory-induced event. He listed possibilities of the origin as either a vaccine or a biomedical weapon.

Dr. Lyons-Weiler has written many articles and three books, many of them are on medical related topics.

“There is, however, clear evidence that the novel sequence, which I will refer to henceforth as INS1378, is from a laboratory-induced recombination event. Specifically,

(1) The sequence similarity to other coronavirus sequences is lower to its most similar sequences in any coronavirus than the rest of the genome (IPAK finding)

(2) The high sequence similarity of INS1378 to a SARS spike protein (2; IPAK Confirmed).

(3) We also found significant sequence similarity of INS1378 to a pShuttle-SN vector that was in use in the 1980’s in China to create a more immunogenic coronavirus (IPAK finding, details below, Option 4).”

He gave four options on the origins of virus:

Option 1. Natural coronavirus related to bat coronaviruses, Not a Recombined Virus. He concluded that this option is a “falsified hypothesis.”

Option 2. A recombined virus that naturally picked up a SARS-like spike protein in its N-terminus of the viral genome. He concluded this option as “speculative hypothesis and unlikely.”

Option 3. A recombined virus made in a laboratory for the purpose of creating a bioweapon.

“Both China and the US hinted at the other side’s potential liability in playing a role in bringing about a novel coronavirus in the lab specifically for the purpose of being used as a bioweapon. To add to the intrigue, a Chinese Scientist had her security access revoked from a BSL-4 laboratory in Manitoba, Canada for violating protocols, allegedly sending samples of deadly viruses to mainland China. On January 26, The Washington Times published an article citing an Israeli defense expert who claimed that China has likely proceeded with a bioweapons program.”

He called it a “rumor” but didn’t reject it from the angle of possibility.

Option 4. A recombined virus made in a laboratory for the purpose of creating a vaccine.

“IPAK researchers found a sequence similarity between a pShuttle-SN recombination vector sequence and INS1378. It turns out that the sequence from pShuttle is most closely related to the Spike protein from SARS coronavirus. This particular technology was used in 2008 to attempt to develop a more immunogenic vaccine against coronavirus.”

Studies reported “serious immunopathology in animals – rats, ferrets, and monkeys – in which animals vaccinated against coronaviruses tended to have extremely high rates of respiratory failure upon subsequent exposure in the study when challenged with the wild-type coronavirus.”

He thinks Option 4 is “most likely.” The Chinese government might have conducted human trials with this vaccine, or this vaccine might have escaped from a lab. “The available evidence most strongly supports that the 2019-NCoV virus is a vaccine strain of coronavirus either accidentally released from a laboratory accident, perhaps a laboratory researcher becoming infected with the virus while conducting animal experiments, or the Chinese were performing clinical studies of a Coronavirus vaccine in humans.”

1. Principia Scientific International, January 31, 2020

On the Origins of the 2019-nCoV Virus, Wuhan, China

2. Washington Times, January 26, 2020
3. James Lyons-Weiler website

James Lyons-Weiler, PhD